Effects of glycogenolysis?

What is the effect of glycogenolysis on the blood sugar? Will it increase it or decrease it. Also what would be the effect on the body if a drug inhibits the release of Norepinephrine at the presynaptic nerve terminal? Thanks, I'm trying to learn pharmacology
Answer:
Glycogen are basically chains of glucose (sugar). Glycogeno + lysis means breakage of glycogen into the smaller pieces of glucose, therefore it increases the quantity of sugar by breaking the chains into the little pieces that form the chain.Nroepinephrine is the neurotransmitter for the Sympathetic Nervous System, which triggers the 'fight or flight' response. Basically it helps you get ready to escape or fight.Here's a list of effects of Norepinephrine as a NT for the Sympathetic Nervous System:Sympathetic nervous system * Diverts blood flow away from the gastro-intestinal (GI) tract and skin via vasoconstriction.
* Blood flow to skeletal muscles, the lung is not only maintained, but enhanced (by as much as 1200%, in the case of skeletal muscles).
* Dilates bronchioles of the lung, which allows for greater alveolar oxygen exchange.
* Increases heart rate and the contractility of cardiac cells (myocytes), thereby providing a mechanism for the enhanced blood flow to skeletal muscles.
* Dilates pupils and relaxes the lens, allowing more light to enter the eye.Inhibition by Beta Blockers:"Beta blockers block the action of endogenous catecholamines (epinephrine (adrenaline) and norepinephrine (noradrenaline) in particular), on 尾-adrenergic receptors, part of the sympathetic nervous system which mediates the "fight or flight" response.There are three known types of beta receptor, designated 尾1, 尾2 and 尾3. 尾1-Adrenergic receptors are located mainly in the heart. 尾2-Adrenergic receptors are located mainly in the lungs, gastrointestinal tract, liver, uterus, vascular smooth muscle, and skeletal muscle. 尾3-receptors are located in fat cells."

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glycogenlysis is the process of breaking down your glycogen, which is like a short term store of energy. your body uses it when your blood sugar is low, say you haven't eaten in a few hours. this is different from gluconeogenesis, which is making glucose from other materials. gluconeogenesis also takes longer to activate. in the end, both processes will raise your blood sugar.not sure if this is the NE question is still about glucose or not, but if it is...NE is used to activate glycogenlysis. since it's part of the sympathetic "fight or flight" system, its role is to say to your body "hey, i'm about to need more glucose for the upcoming fight." thus, if the NE is blocked, it won't generate the appropriate response of raising your blood sugar to meet your metabolic needs.

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